Publications

Please find the full list of publications at google scholar: Tuo Wang

Click on the title of each paper for the PDF file or weblink.

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98. A Jacob, W Qi, JR Yarava, M Barkarar, A Karai, JV Vermaas, JR Kohler, T Wang. Oxidative stress-responsive cell wall remodeling depends on phosphate in Candida albicans. Submitted.

100. K Singh, A Ankur, JR Yarava, CM Fernandes, G Vascelli, A Sulla, T Zelante, M Del Poeta, T Wang. α-1,3-Glucan-Driven Remodeling of the Conidial Cell Wall in an Aspergillus fumigatus Vaccine Strain Alters Innate Immune Recognition. Submitted. Available at BioRxiv. 

99. R Sharma, D Parashar, M Nokab, A Jacob, T Wang, S Puri. A novel role for signaling mucin Msb2 in maintaining iron homeostasis in Candida albicans. Submitted.

98. Y Cai, C Ronders, V Mottini, H Yuan, S Kalpana, L, Xing, I Singh, D Fu, K Zhao, L Heller, K Nguyen, B Waller, T Wang, G Bonito, J Li. Mycoelectronics: bioprinted living fungal bioelectronics for artificial sensation. Submitted.

97. M Nokab, C Vojvodin, O Alghazwat, EA Zeitoun, M Vanderveken, E Caron, I Gautam, D Debnath, BK Husband, FL Hatton, C Martin-Olmos, FH Marchesini, T Wang, KO Sebakhy. Tuning alginate and pectin hydrogels: effects of solution viscosity and crosslinking ions revealed by solid-state NMR and rheology. Submitted.

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91. I Gautam, A Ankur, K Singh, A Jacob, TL Doering, NAR Gow, JP Latge, T Wang. Breaking down the wall: solid-state NMR illuminates how fungi build and remodel diverse cell walls.

89. A Ankur, JR Yavara, I Gautam, FJ Scott, F Mentink-Vigier, C Chrissian, L Xie, D Roy, RE Stark, TL Doering, P Wang, T Wang. Polymorphic α-glucans as structural scaffolds in Cryptococcus cell walls for chitin, capsule, and melanin: Insights from 13C and 1H solid-state NMR.

64. W Zhao, D Debnath, I Gautam, LD Fernando, T Wang. Charting the Solid-State NMR Signals of Polysaccharides: A Database-Driven Roadmap. Magn. Reson. Chem. 62, 298-309 (2024). invited article for the glycoNMR special issue.

63.

61. LD Fernando, W Zhao, I Gautam, A Ankur, T Wang. Polysacchride Assemblies in Fungal and Plant Cell Walls Explored by Solid-State NMR. Structure 31, 1375-1385 (2023). Invited for the 30th anniversary issue.

60. W Zhao, F Deligey, SC Shekar, F Mentink-Vigier, T Wang. Current limitations of solid-state NMR in carbohydrate and cell wall research. J. Magn. Reson. 341, 107263 (2022). Invited article. Special issue: ISMAR feature articles.

59. LD Fernando, MC Dickwella Widanage, SC Shekar, F Mentink-Vigier, T Wang. Solid-state NMR analysis of unlabeled fungal cell walls from Aspergillus and Candida species. J. Struct. Biol. X 6, 100070 (2022). Invited article. Special issue: structure by SSNMR.

58. JP Latge, T Wang. Modern biophysics redefines our understanding of fungal cell wall structure, complexity and dynamics. mBio 13, e01145-22 (2022).

57. F Deligey, M Frank, SH Cho, A Kirui, F Mentink-Vigier, M Swulius, BT Nixon, T Wang. Structure of in-vitro synthesized cellulose fibrils viewed by cryo-electron tomography and 13C natural-abundance dynamic nuclear polarization. Biomacromolecules, 23, 2290-2301 (2022). Supplementary journal cover.

56. A Kirui, W Zhao, F Deligey, H Yang, X Kang, F Mentink-Vigier, T Wang. Carbohydrate-aromatic interface and molecular architecture of lignocellulose. Nat. Commun. 13, 538 (2022). Selected as editors’ highlight and highlighted on EurekAlert!, National MagLab, and DOE office of science webpage.

55. S Chandra Shekar, W Zhao, LD Fernando, I Hung, T Wang. A three-dimensional 13C-13C-13C DQ-SQ-SQ correlation experiment for high-resolution analysis of complex carbohydrates using solid-state NMR. J. Magn. Reson. 336, 107148 (2022). Invited article. Special issue: new voices in magnetic resonances.

54. N Ghassemi, A Poulhazan, F Deligey, F Mentink-Vigier, I Marcotte, T Wang. Solid-state NMR investigations of extracellular matrices and cell walls of algae, bacteria, fungi, and plants. Chem. Rev. 122, 1003610086 (2022). Invited article. Supplementary journal cover.

53. Z Ling, W Tang, Y Su, C Huang, A Kirui, T Wang, AD French, Q Yong. Stepwise allomorphic transformations by alkaline and ethylenediamine treatments on bamboo crystalline cellulose for enriched enzymatic digestibility. Ind. Crops Prod.177, 114450 (2022)

52. S Chandra Shekar, W Zhao, TK Weldeghiorghis, T Wang. Effect of cross polarization radiofrequency phases on signal phases. Solid State Nucl. Magn. Reson. 117, 101771 (2022).

51. A Chakraborty, LD Fernando, W Fang, MC Dickwella Widanage, P Wei, C Jin, T Fontaine, J-P Latge, T Wang. A molecular vision of fungal cell wall organization by functional genomics and solid-state NMR. Nat. Commun.12, 6346 (2021).Check out the story on Analytical Scientist, EurekAlert! and National MagLab.

50. A Poulhazan, M Dickwella Widanage, A Muszynski, A Arnold, D Warschawsi, A Parastoo, M Isabelle, T Wang. Identification and quantification of glycans in whole cells: architecture of microalgal polysaccharides described by solid-state NMR. J. Am. Chem. Soc. 143, 46, 19374-388 (2021). Highlighted on the front cover.

49. LD Fernando, MC Dickwella Widanage, J Penfield, AS Lipton, N Washton, J-P Latge, P Wang, L Zhang, T Wang. Structural polymorphism of chitin and chitosan in fungal cell walls from solid-state NMR and principal component analysis. Front. Mol. Biosci. 8, 727053 (2021). Invited article.

48. A Kirui, J Du, W Zhao, W Barnes, X Kang, C. Anderson, C Xiao, T Wang. A pectin methyltransferase modulates polysaccharide dynamics and interactions in Arabidopsis primary cell walls: evidence from solid-state NMR. Carbohydr. Polym. 270, 118370 (2021).

47. W Zhao, A Kirui, F Deligey, F Mentink-Vigier, Y Zhou, B Zhang, T Wang. Solid-state NMR of unlabeled plant cell walls: high-resolution structrual analysis without isotopic enrichment. Biotechnol. Biofuels 14:14, (2021).

46. L Wilson, F Deligey, T Wang, DJ Cosgrove. Saccharide analysis of onion outer epidermal walls. Biotechnol. Biofuels 14: 66 (2021).

45. B Addison, D Stengel, VS Bharadwaj, RM Happs, C Doeppke, T Wang, YJ Bomble, GP Holland, AE Harman-Ware. Selective one-dimensional 13C–13C spin-diffusion solid-state nuclear magnetic resonance methods to probe spatial arrangements in biopolymers including plant cell walls, peptides, and spider silk. J. Phys. Chem. B 124, 44, 9870–9883 (2020). Front cover ariticle.

44. J Du, A Kirui, S Huang, L Wang, WJ Barnes, SN Kiemle, Y Zheng, Y Rui, M Ruan, S Qi, SH Kim, T Wang., DJ Cosgrove, CT Anderson, C Xiao. Mutations in the pectin methyltransferase QUASIMODO2 influence cellulose biosynthesis and wall integrity in Arabidopsis thaliana. Plant Cell 2:3576–3597 (2020). 

43. A Chakraborty, F Deligey, J Quach, F. Mentink-Vigier, P. Wang, T Wang. Biomolecular complex viewed by dynamic nuclear polarization solid-state NMR spectroscopy. Biochem. Soc. Trans. 48, 1089-1099 (2020). Invited article.

42. LD Fernando, W Zhao, MC Dickwella Widanage, F. Mentink-Vigier, T Wang. Solid-state NMR and DNP investigations of carbohydrates and cell wall biomaterials. eMagRes 9, 251-259 (2020). Invited article.

41. M Liu, Z Zhang, C Ding, T Wang, BL Kelly, P Wang. Transcriptomic analysis of extracellular RNA governed by the endocytic adaptor protein Cin1 of Cryptococcus deneoformans. Front. Cell. Infect. Microbiol. 10:256 (2020).

40. W Zhao, LD Fernando, A Kirui, F Deligey, T Wang. Solid-state NMR of plant and fungal cell walls: a critical review. Solid State Nucl. Magn. Reson. 107, 101660 (2020). Invited Trends article.

39. X Kang, W Zhao, MC Dickwella Widanage, A Kirui, U Ozdenvar, T Wang. CCMRD: a solid-state NMR database for complex carbohydrates. J. Biomol. NMR 74, 239-250 (2020).

38. X Kang, C Elson, J Penfield, A Kirui, A Chen, L Zhang, T Wang. Integrated solid-state NMR and molecular dynamics modeling determines membrane insertion of human β-defensin analog. Commun. Biol. 2: 402 (2019).

37. L Zhang, C Gao, F. Mentink-Vigier, L Tang, D. Zhang, S Wang, S Cao, Z Xu, X Liu, T Wang, Y Zhou, B Zhang. Arabinosyl deacetylase modulates the arabinoxylan acetylation profile and secondary wall formation. Plant Cell 31, 1113–1126 (2019).

36.  X Kang, A Kirui, MC Dickwella Widanage, F Mentink-Vigier, DJ Cosgrove, T Wang. Lignin-polysaccharide interactions in plant secondary cell walls revealed by solid-state NMR. Nat. Commun. 10, 347, (2019). Check out the story on Science DailyPhys.org, EurekAlert! and National MagLab.

35.  Z Ling, T Wang, M Makarem, MS Cintron, HN Cheng, X Kang, M Bacher, A Potthast, T Rosenau, H King, CD Delhom, S Nam, JV Edwards, SH Kim, F Xu, AD French. Effects of ball milling on the structure of cotton cellulose. Cellulose 26, 305-328 (2019).

34.  A Kirui, Z Ling, X Kang, MC Dickwella Widanage, F Mentink-Vigier, AD French, T Wang. Atomic resolution of cotton cellulose structure enabled by dynamic nuclear polarization solid-state NMR. Cellulose 26, 329-339 (2019). 

33.  A Kirui, MC Dickwella Widanage, F Mentink-Vigier, P Wang, X Kang, T Wang. Preparation of fungal and plant materials for structural elucidation using dynamic nuclear polarization solid-state NMR. J. Vis. Exp. 144, e59152 (2019). 1Equal contribution.

32. X Kang, A Kirui, A Muszyński, MC Dickwella Widanage, A Chen, P Azadi, P Wang, F Mentink-Vigier, T Wang. Molecular architecture of fungal cell walls revealed by solid-state NMR. Nat. Commun. 9, 2747 (2018). Check out the story on LSU News, Science Daily, Phys.org and EurekAlert!

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31. P Phyo, T Wang, Y Yang, H O’Neill, M Hong. Direct determination of hydroxymethyl conformations of plant cell wall cellulose using 1H polarization transfer solid-state NMR. Biomacromolecules 19,1485–1497 (2018).

30. M Roos, T Wang, A , M Hong. Fast magic-angle-spinning 19F spin exchange NMR for determining nanometer 19F-19F distances in proteins and pharmaceutical compounds. J. Phys. Chem. B 122, 2900-2911 (2018).

29. H Yang, T Wang, D Oehme, L Petridis, M Hong, JD Kubicki. Structural factors affecting 13C NMR chemical shifts of cellulose: a computational study. Cellulose 25, 23-36 (2018).

28. P Phyo*, T Wang*, SN Kiemle*, H O’Neill, SV Pingali, M Hong, DJ Cosgrove. Gradients in wall mechanics and polysaccharides along growing Arabidopsis inflorescence stems. Plant Physiol. 175, 1593-1607 (2017). (*) denotes equal contribution.

27. P Phyo, T Wang, C Xiao, C Anderson, M Hong. Effects of pectin molecular-weight changes on the structure, dynamics and polysaccharide interactions of primary cell walls of Arabidopsis thaliana: insights from solid-state NMR. Biomacromolecules 18, 2937-2950 (2017).

26. T Wang, H Jo, WF DeGrado, M Hong. Water distribution, dynamics and interactions with alzheimer’s beta-amyloid fibrils investigated by solid-state NMR. J. Am. Chem. Soc. 139, 6242-6252 (2017).

25. M Lee, T Wang, OV Makhlynets, Y Wu, N Polizzi, H Wu, PM Gosavi, IV Korendovych, WF DeGrado, M Hong. Zinc-binding structure of a catalytic amyloid from solid-state NMR spectroscopy. Proc. Natl. Acad. Sci. USA 114, 6191-6196 (2017).

24. MD Gelenter, T Wang, S Liao, H O’Neill, M Hong. 2H-13C correlation solid-state NMR for investigating dynamics and water accessibilities of proteins and carbohydrates. J. Biomol. NMR 68, 257-270 (2017).

23. T Wang*, Y Chen*, A Tabuchi, DJ Cosgrove, M Hong. The target of expansin EXPB1 in maize cell walls from binding and solid-state NMR studies. Plant Physiol. 172, 2107-2119. (2016) (*) equal contribution.

22. M Elkins*, T Wang*, M Nick, H Jo, T Lemmin, S Prusiner, WF DeGrado, J Stohr, M Hong. Structural polymorphism of alzheimer’s beta-amyloid fibrils as controlled by an E22 switch: a solid-state NMR study. J. Am. Chem. Soc. 138, 9840-9852 (2016). (*) equal contribution.

21.  T Wang, H Yang, JD Kubicki and M Hong. Cellulose structural polymorphism in plant primary cell walls investigated by high-field 2D solid-state NMR spectroscopy and density functional theory calculations. Biomacromolecules 17, 2210-2222 (2016).

20. T Wang, P Phyo, M Hong. Multidimensional solid-state NMR spectroscopy of plant cell walls. Solid State Nucl. Magn. Reson. 78, 56-63 (2016). Invited Trend article.

19. T Wang and M Hong. Structure and dynamics of polysaccharides in plant cell walls from solid-state NMR. Invited Book Chapter for NMR in Glycoscience and Glycotechnology, Royal Society of Chemistry.

18. SY Liao, M Lee, T Wang, I Sergeyev and M Hong. Efficient DNP NMR of membrane proteins: sample preparation protocols, sensitivity, and radical location. J. Biomol. NMR 64, 223-237 (2016).

17. T Wang and M Hong. Solid-state NMR investigations of cellulose structure and interactions with matrix polysaccharides in plant primary cell walls. J. Exp. Bot. 67, 503-514 (2016). Invited paper.

16. T Wang, YB Park, DJ Cosgrove, M Hong. Cellulose-pectin spatial contacts are inherent to never-dried Arabidopsis thaliana primary cell walls: evidence from solid-state NMR. Plant Physiol. 168, 871-884 (2015).

15. T Wang and M Hong. Investigation of the curvature generation and membrane localization of the influenza virus M2 protein using static and off-magic-angle spinning solid-state NMR spectroscopy of oriented bicelles. Biochemistry 54, 2214-2226 (2015).

14. T Wang, JK Williams, K Schmidt-Rohr, M Hong. Relaxation-compensated difference spin diffusion NMR for detecting 13C-13C long-range correlations in proteins and polysaccharidesJ. Biomol. NMR 61, 97-107 (2015).

13. PB White*, T Wang*, YB Park, DJ Cosgrove, M Hong. Water-polysaccharide interactions in the primary cell wall of Arabidopsis thaliana from polarization transfer solid-state NMR. J. Am. Chem. Soc. 136, 10399-10409 (2014). (*) denotes equal contribution. 

12. NH Joh, T Wang, MP Bhate, R Acharya, Y Wu, M Grabe, M Hong, G Grigoryan, WF DeGrado. De novo design of a transmembrane Zn2+ transporting four-helix bundle. Science 346, 1520-1524 (2014). Featured in the same issue’s Perspective, Nature Chemistry, C&EN,  EurekAlert, technology.org, F1000, etc.

11. T Wang, A Salazar, O Zabotina, M Hong. Structure and dynamics of Brachypodium primary cell walls polysaccharides from 2D 13C solid-state NMR spectroscopy. Biochemistry 53, 2840-2854 (2014).

10. T Wang, YB Park, MA Caporini, M Rosay, L Zhong. DJ Cosgrove, M Hong. Sensitivity-enhanced solid-state NMR detection of expansin’s target in plant cell walls. Proc. Natl. Acad. Sci. USA 110, 16444-16449 (2013).

9. T Wang, H Yao, M Hong. Determining the depth of insertion of dynamically invisible membrane peptides by gel-phase 1H spin diffusion heteronuclear correlation NMR. J. Biomol. NMR 56, 139-148 (2013).

8. T Wang, O Zabotina, M Hong. Pectin–Cellulose Interactions in the Arabidopsis Primary Cell Wall from Two-Dimensional Magic-Angle-Spinning Solid-State Nuclear Magnetic Resonance. Biochemistry 51, 9846-9856 (2012).

7. T Wang, L Widanapathirana, Y Zhao, M Hong. Aggregation and dynamics of oligocholate transporters in phospholipid bilayers reealed by solid-state NMR spectroscopy. Langmuir 28, 17071-17078 (2012).

6. T Wang, SD Cady, M Hong. NMR determination of protein partitioning into membrane domains with different curvatures and application to the influenza M2 protein. Biophys. J. 102, 787-794 (2012).

5. DM Harris, K Corbin, T Wang, R Gutierrez, AL Bertolo, C Petti, DM Smilgies, JM Estevez, D Bonetta, B Urbanowicz, D Ehrhardt, CR Somerville, JKC Rose, M Hong, S DeBolt. Cellulose microfibril crystallinity is reduced by mutating C-terminal transmembrane region residues CESA1A903V and CESA3T942I of cellulose synthase. Proc. Natl. Acad. Sci. USA 109, 4098-4103 (2012).

4. M Dick-Perez, T Wang, A Salazar, O Zabotina, M Hong. Multidimensional solid-state NMR studies of the structure and dynamics of pectic polysaccharides in uniformly 13C-labeled Arabidopsis primary cell walls. Magn. Reson. Chem. 50, 539-550 (2012).

3. SD Cady, T Wang, M Hong. Membrane-dependent effects of a cytoplasmic helix on the structure and drug binding of the influenza M2 protein”, J. Am. Chem. Soc. 133, 11572-11579 (2011).

2. J Wang, C Ma, G Fiorin, V Carnevale, T Wang, F Hu, RA Lamb, ML Klein, LH Pinto, M Hong, WF DeGrado. Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2. J. Am. Chem. Soc. 133, 12834-12841 (2011).

1. YS Liu, JY Zhou, XL Zhan, ZB Liu, XJ Wan, JG Tian, T Wang, YS Chen. Synthesis, characterization and optical limiting property of covalently oligothiophene-functionalized graphene material. Carbon 47, 3113-3121, (2009).

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